The Science of Pain Relief: How THC and CBD Work Together. THC (tetrahydrocannabinol) and CBD (cannabidiol) are two well-known compounds in cannabis that help relieve pain. In this post, we’ll delve into how each manages to provide relief across the body and how effective they are when combined.
How THC Relieves Pain/The Science of Pain Relief: How THC and CBD Work Together
THC helps manage pain by interacting with the body’s endocannabinoid system (ECS), which regulates pain. The ECS consists of receptors, enzymes, and naturally produced cannabinoids. THC binds to these receptors and can reduce pain by blocking pain signals in the spine and brain, offering relief for both mind and body. THC also minimizes inflammation, which can lower the sensation of pain.
How CBD Relieves Pain Differently
While CBD also engages with the ECS, it doesn’t bind to the pain receptors like THC does. Instead, CBD raises the levels of anandamide, a cannabinoid that helps reduce pain and inflammation across the body. Additionally, CBD interacts with other receptors like serotonin and vanilloid, further contributing to pain relief.
The Synergistic Effectiveness of THC and CBD
Although research on cannabis is still limited, existing scientific evidence shows its promise. A 2018 review found that both THC and CBD can reduce pain and improve sleep for chronic pain sufferers. Another review in 2015 found CBD effective against a range of pain-related conditions. While more studies are needed, the current findings are encouraging.
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